Summary of Insulin Section

It is difficult to summarize the insulin section, but shown below are charts with the basic pharmacodynamics of the current insulins.  As will be discussed fully in the management section, in general, long acting insulin such as insulin glargine, is used as basal insulin to control hepatic gluconeogenesis.  Short acting insulin, such as insulin aspart, is given just before a meal to give physiologic insulin coverage for that meal.

 

 

Current Premixed Insulins

Insulin Name
First Component
Second Component
Component Ratio  
First:Second
Novolin 70/30
Human NPH
Human Regular
70:30
Novolog 70/30
aspart protamine
aspart
70:30
Humulin 70/30
Human NPH
Human Regular
70:30
Humalog 50/50
apart
protamine
aspart
50:50
Humalog 75/25
lispro protamine
lispro
75:25